- Cheapest fare
- $351
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 8h 55m
avianca airlines · Fri, Nov 6
from $351
Usually 1+ stop
5,090 km
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Cheapest month to fly from Panama City to Sao Paulo
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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Getting around
About flights from Panama City to Sao Paulo
Panama City (PTY) and Sao Paulo (SAO) are about 5,090 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 8h 55m. Over the next few months, one-way fares start from $351, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Panama City to Sao Paulo?
The cheapest one-way fare we've seen recently is $351 with avianca airlines, departing Friday, November 6, 2026. Over the coming months, the lowest fare in each month ranges from $351 to $387.
What is the cheapest month to fly from Panama City to Sao Paulo?
November 2026 currently has the lowest fares, from $351 one way.
Are there direct flights from Panama City to Sao Paulo?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Panama City to Sao Paulo?
The quickest journey we've seen takes about 8h 55m. Panama City and Sao Paulo are around 5,090 km apart.
Which airlines fly from Panama City to Sao Paulo?
Recent fares on this route were with avianca airlines.
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