Copa AirlinesDepart01:40
Wed, Nov 4GRU → SDQ
9h 29m · 1 stop
$389one way, per person
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- Cheapest fare
- $389
- Cheapest month
- November
- Direct flights
- Not recently
- Quickest trip
- 9h 14m
Copa Airlines · Wed, Nov 4
from $389
Usually 1+ stop
5,310 km
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Cheapest month to fly from Sao Paulo to Santo Domingo
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
Copa Airlines
LATAM Airlines BrasilDepart21:35
Mon, Nov 9GRU → SDQ
14h 10m · 3 stops
$583one way, per person
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Plan the rest of your trip to Santo Domingo
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About flights from Sao Paulo to Santo Domingo
Sao Paulo (SAO) and Santo Domingo (SDQ) are about 5,310 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 9h 14m. Over the next few months, one-way fares start from $389, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Sao Paulo to Santo Domingo?
The cheapest one-way fare we've seen recently is $389 with Copa Airlines, departing Wednesday, November 4, 2026. Over the coming months, the lowest fare in each month ranges from $389 to $395.
What is the cheapest month to fly from Sao Paulo to Santo Domingo?
November 2026 currently has the lowest fares, from $389 one way.
Are there direct flights from Sao Paulo to Santo Domingo?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Sao Paulo to Santo Domingo?
The quickest journey we've seen takes about 9h 14m. Sao Paulo and Santo Domingo are around 5,310 km apart.
Which airlines fly from Sao Paulo to Santo Domingo?
Recent fares on this route were with Copa Airlines and LATAM Airlines Brasil.
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