Cheap flights from Cusco to Medellin

One-way fares from $116 · CUZ → MDE · prices found by travellers in the last 48 hours

Compare all dates Medellin → Cusco
Cheapest fare
$116

JetSmart · Wed, Nov 11

Cheapest month
November

from $116

Direct flights
Not recently

Usually 1+ stop

Quickest trip
4h 51m

2,240 km

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Cheapest month to fly from Cusco to Medellin

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $116
  2. January 2027 $202

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart21:30 Wed, Nov 11CUZ → MDE 4h 51m · 1 stop
$116one way, per person
View deal
See every date in November 2026 →

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Getting around

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About flights from Cusco to Medellin

Cusco (CUZ) and Medellin (MDE) are about 2,240 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 51m. Over the next few months, one-way fares start from $116, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Cusco to Medellin?

The cheapest one-way fare we've seen recently is $116 with JetSmart, departing Wednesday, November 11, 2026. Over the coming months, the lowest fare in each month ranges from $116 to $202.

What is the cheapest month to fly from Cusco to Medellin?

November 2026 currently has the lowest fares, from $116 one way.

Are there direct flights from Cusco to Medellin?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Cusco to Medellin?

The quickest journey we've seen takes about 4h 51m. Cusco and Medellin are around 2,240 km apart.

Which airlines fly from Cusco to Medellin?

Recent fares on this route were with JetSmart and Sky Airline.

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