Sky AirlineDepart21:05
Fri, Feb 26CUZ → VVI
4h 20m · 1 stop
$220one way, per person
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- Cheapest fare
- $220
- Cheapest month
- February
- Direct flights
- Not recently
- Quickest trip
- 4h 20m
Sky Airline · Fri, Feb 26
from $220
Usually 1+ stop
1,050 km
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Cheapest month to fly from Cusco to Santa Cruz
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in February 2027
The lowest fares we've seen for each day, cheapest first.
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About flights from Cusco to Santa Cruz
Cusco (CUZ) and Santa Cruz (SRZ) are about 1,050 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 4h 20m. Over the next few months, one-way fares start from $220, and February 2027 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Cusco to Santa Cruz?
The cheapest one-way fare we've seen recently is $220 with Sky Airline, departing Friday, February 26, 2027.
What is the cheapest month to fly from Cusco to Santa Cruz?
February 2027 currently has the lowest fares, from $220 one way.
Are there direct flights from Cusco to Santa Cruz?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Cusco to Santa Cruz?
The quickest journey we've seen takes about 4h 20m. Cusco and Santa Cruz are around 1,050 km apart.
Which airlines fly from Cusco to Santa Cruz?
Recent fares on this route were with Sky Airline.
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