Cheap flights from Guayaquil to Panama City

One-way fares from $180 · GYE → PTY · prices found by travellers in the last 48 hours

Compare all dates Panama City → Guayaquil
Cheapest fare
$180

avianca airlines · Mon, Dec 7

Cheapest month
December

from $180

Direct flights
Yes

Copa Airlines

Flight time
2h 17m

1,240 km

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Cheapest month to fly from Guayaquil to Panama City

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 $189
  2. December 2026 Cheapest $180

Cheapest dates in December 2026

The lowest fares we've seen for each day, cheapest first.

avianca airlines
Depart19:35 Mon, Dec 7GYE → PTY 3h 45m · 1 stop
$180one way, per person
View deal
Copa Airlines
Depart12:22 Mon, Dec 28GYE → PTY 2h 17m · Direct
$200one way, per person
View deal
See every date in December 2026 →

Plan the rest of your trip to Panama City

Where to stay, what to do and getting around, from our travel partners.

Where to stay

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Things to do

Things to do in Panama CityTours, attractions and day trips on Klook Explore →

Getting around

Airport transfer in Panama CityPre-book a driver to meet you at arrivals, with Kiwitaxi Book a transfer → Car hire in Panama CityCompare rental cars from major brands on EconomyBookings Compare cars →

About flights from Guayaquil to Panama City

Guayaquil (GYE) and Panama City (PTY) are about 1,240 km apart. Direct flights take around 2h 17m, and recent direct fares were with Copa Airlines. Over the next few months, one-way fares start from $180, and December 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Guayaquil to Panama City?

The cheapest one-way fare we've seen recently is $180 with avianca airlines, departing Monday, December 7, 2026. Over the coming months, the lowest fare in each month ranges from $180 to $189.

What is the cheapest month to fly from Guayaquil to Panama City?

December 2026 currently has the lowest fares, from $180 one way.

Are there direct flights from Guayaquil to Panama City?

Yes. Recent direct fares were with Copa Airlines.

How long is the flight from Guayaquil to Panama City?

A direct flight takes about 2h 17m. Guayaquil and Panama City are around 1,240 km apart.

Which airlines fly from Guayaquil to Panama City?

Recent fares on this route were with avianca airlines and Copa Airlines.

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