JetSmartDepart18:23
Thu, Nov 12LSC → ANF
1h 27m · Direct
$24one way, per person
View deal
- Cheapest fare
- $24
- Cheapest month
- November
- Direct flights
- Yes
- Flight time
- 1h 23m
JetSmart · Thu, Nov 12
from $24
JetSmart and Sky Airline
700 km
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Cheapest month to fly from La Serena to Antofagasta
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
JetSmart
Sky AirlineDepart11:37
Fri, Nov 13LSC → ANF
1h 23m · Direct
$25one way, per person
View deal
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About flights from La Serena to Antofagasta
La Serena (LSC) and Antofagasta (ANF) are about 700 km apart. Direct flights take around 1h 23m, and recent direct fares were with JetSmart and Sky Airline. Over the next few months, one-way fares start from $24, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from La Serena to Antofagasta?
The cheapest one-way fare we've seen recently is $24 with JetSmart, departing Thursday, November 12, 2026.
What is the cheapest month to fly from La Serena to Antofagasta?
November 2026 currently has the lowest fares, from $24 one way.
Are there direct flights from La Serena to Antofagasta?
Yes. Recent direct fares were with JetSmart and Sky Airline.
How long is the flight from La Serena to Antofagasta?
A direct flight takes about 1h 23m. La Serena and Antofagasta are around 700 km apart.
Which airlines fly from La Serena to Antofagasta?
Recent fares on this route were with JetSmart and Sky Airline.