Sky AirlineDepart21:59
Thu, Nov 12LSC → SCL
1h 01m · Direct
$27one way, per person
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- Cheapest fare
- $27
- Cheapest month
- November
- Direct flights
- Yes
- Flight time
- 1h 01m
Sky Airline · Thu, Nov 12
from $27
Sky Airline
400 km
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Cheapest month to fly from La Serena to Santiago
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in November 2026
The lowest fares we've seen for each day, cheapest first.
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About flights from La Serena to Santiago
La Serena (LSC) and Santiago (SCL) are about 400 km apart. Direct flights take around 1h 01m, and recent direct fares were with Sky Airline. Over the next few months, one-way fares start from $27, and November 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from La Serena to Santiago?
The cheapest one-way fare we've seen recently is $27 with Sky Airline, departing Thursday, November 12, 2026.
What is the cheapest month to fly from La Serena to Santiago?
November 2026 currently has the lowest fares, from $27 one way.
Are there direct flights from La Serena to Santiago?
Yes. Recent direct fares were with Sky Airline.
How long is the flight from La Serena to Santiago?
A direct flight takes about 1h 01m. La Serena and Santiago are around 400 km apart.
Which airlines fly from La Serena to Santiago?
Recent fares on this route were with Sky Airline.