Cheap flights from Antofagasta to La Serena

One-way fares from $47 · ANF → LSC · prices found by travellers in the last 48 hours

Compare all dates La Serena → Antofagasta
Cheapest fare
$47

JetSmart · Thu, Nov 12

Cheapest month
November

from $47

Direct flights
Yes

JetSmart

Flight time
1h 27m

700 km

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Cheapest month to fly from Antofagasta to La Serena

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $47

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

JetSmart
Depart16:23 Thu, Nov 12ANF → LSC 1h 27m · Direct
$47one way, per person
View deal
See every date in November 2026 →

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Where to stay, what to do and getting around, from our travel partners.

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Things to do

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Getting around

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About flights from Antofagasta to La Serena

Antofagasta (ANF) and La Serena (LSC) are about 700 km apart. Direct flights take around 1h 27m, and recent direct fares were with JetSmart. Over the next few months, one-way fares start from $47, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Antofagasta to La Serena?

The cheapest one-way fare we've seen recently is $47 with JetSmart, departing Thursday, November 12, 2026.

What is the cheapest month to fly from Antofagasta to La Serena?

November 2026 currently has the lowest fares, from $47 one way.

Are there direct flights from Antofagasta to La Serena?

Yes. Recent direct fares were with JetSmart.

How long is the flight from Antofagasta to La Serena?

A direct flight takes about 1h 27m. Antofagasta and La Serena are around 700 km apart.

Which airlines fly from Antofagasta to La Serena?

Recent fares on this route were with JetSmart.

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