Cheap flights from Antofagasta to Guayaquil

One-way fares from $320 · ANF → GYE · prices found by travellers in the last 48 hours

Compare all dates Guayaquil → Antofagasta
Cheapest fare
$320

Sky Airline · Tue, Nov 10

Cheapest month
November

from $320

Direct flights
Not recently

Usually 1+ stop

Quickest trip
11h 07m

2,600 km

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Cheapest month to fly from Antofagasta to Guayaquil

Lowest one-way fare per person in each month. Choose a month to see every date.

  1. November 2026 Cheapest $320

Cheapest dates in November 2026

The lowest fares we've seen for each day, cheapest first.

Sky Airline
Depart20:00 Tue, Nov 10ANF → GYE 11h 07m · 2 stops
$320one way, per person
View deal
See every date in November 2026 →

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Getting around

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About flights from Antofagasta to Guayaquil

Antofagasta (ANF) and Guayaquil (GYE) are about 2,600 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 11h 07m. Over the next few months, one-way fares start from $320, and November 2026 is currently the cheapest month to fly.

These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.

Frequently asked questions

How much is a flight from Antofagasta to Guayaquil?

The cheapest one-way fare we've seen recently is $320 with Sky Airline, departing Tuesday, November 10, 2026.

What is the cheapest month to fly from Antofagasta to Guayaquil?

November 2026 currently has the lowest fares, from $320 one way.

Are there direct flights from Antofagasta to Guayaquil?

We haven't seen direct fares recently, so most journeys include at least one stop.

How long is the flight from Antofagasta to Guayaquil?

The quickest journey we've seen takes about 11h 07m. Antofagasta and Guayaquil are around 2,600 km apart.

Which airlines fly from Antofagasta to Guayaquil?

Recent fares on this route were with Sky Airline.

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