avianca airlinesDepart10:05
Tue, Dec 22PTY → MDE
2h 40m · 1 stop
$216one way, per person
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- Cheapest fare
- $216
- Cheapest month
- December
- Direct flights
- Not recently
- Quickest trip
- 2h 35m
avianca airlines · Tue, Dec 22
from $216
Usually 1+ stop
530 km
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Cheapest month to fly from Panama City to Medellin
Lowest one-way fare per person in each month. Choose a month to see every date.
Cheapest dates in December 2026
The lowest fares we've seen for each day, cheapest first.
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Where to stay, what to do and getting around, from our travel partners.
Getting around
About flights from Panama City to Medellin
Panama City (PTY) and Medellin (MDE) are about 530 km apart. We haven't seen direct fares on this route recently, so expect at least one stop; the quickest journey we've seen takes about 2h 35m. Over the next few months, one-way fares start from $216, and December 2026 is currently the cheapest month to fly.
These prices come from searches travellers made in the last 48 hours, so they move quickly. If you see a good fare, it's worth booking soon. FlightsExp is free to use: you book directly with our travel partner.
Frequently asked questions
How much is a flight from Panama City to Medellin?
The cheapest one-way fare we've seen recently is $216 with avianca airlines, departing Tuesday, December 22, 2026. Over the coming months, the lowest fare in each month ranges from $216 to $229.
What is the cheapest month to fly from Panama City to Medellin?
December 2026 currently has the lowest fares, from $216 one way.
Are there direct flights from Panama City to Medellin?
We haven't seen direct fares recently, so most journeys include at least one stop.
How long is the flight from Panama City to Medellin?
The quickest journey we've seen takes about 2h 35m. Panama City and Medellin are around 530 km apart.
Which airlines fly from Panama City to Medellin?
Recent fares on this route were with avianca airlines.
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